![]() ![]() Key variables were tested in the sensitivity analysis. ![]() The BIM showed the difference of expenditure and clinical events (intracranial hemorrhage or major extracranial bleeding) generated by the base case calculated for current prescription volumes (D150 30%, R20 100%), and for different prescription volume scenarios (D150 at 70% and 100%). Ex-factory prices and National Tariffs were considered to estimate the costs of drugs and medical resource used, respectively. Only direct medical costs were considered. The resource utilization (drugs and intracranial hemorrhage or major extracranial bleeding event) was derived from an observational study. METHODS: A budget-impact model (BIM) was developed to estimate the direct costs up to 12 months from an Italian NHS perspective. OBJECTIVE: This analysis estimated the budget impact of the use of D150 and R20 for the treatment of NAFV patients in Italy. Outcomes from observational study demonstrated that D150 and R20 reduced the rate of thromboembolic events. Cardiologia, Ospedale Santa Croce e Carle, Cuneo, Italyĥ Health Publishing & Services Srl, Milan, ItalyīACKGROUND: Dabigatran 150 mg BID (D150) and rivaroxaban 20 mg (R20) are indicated for the prevention of thromboembolic events in patients with Non-Valvular Atrial Fibrillation (NVAF). Azienda Ospedaliera San Giovanni Addolorata, Rome, Italyģ Dipartimento Cardiotoracico Azienda Sanitaria Universitaria Integrata di Udine, Udine, ItalyĤ S.C. Maria Grazia Celeste 1, Francesca De Marco 2, Claudio Fresco 3, Giuseppe Musumeci 4, Roberto Ravasio 5ġ UOC Farmacia Clinica, Fondazione PTV Policlinico Tor Vergata, Rome, ItalyĢ UOC Pronto Soccorso e Breve Osservazione. ![]() Health economics and therapeutic pathways 2017 18(1): -111īudget impact analysis of dabigatran compared with rivaroxaban in the prevention of the thromboembolic risk in patients with non-valvular atrial fibrillation ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |